Product Name:

NebuSelect™ Recombinant Biotinylated Human Siglec-5/CD170 , hFc-tag

Catalog#:

NBL-242114

Description:

NebuSelect™ Recombinant Biotinylated Human Siglec-5/CD170 , hFc-tag(Cat#NBL-242114) is expressed in HEK293 with hFc tag at the C-Terminus.It contains Glu17-Thr434.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 73.1 kDa. Due to glycosylation, the protein migrates to 90-115 kDa based on Bis-Tris PAGE result.

Target Name:

Siglec-5/CD170; CD170; CD33 antigen-like 2; CD33L2; OBBP2; Siglec5; SIGLEC5; OB-BP2

Target Information:

Group B Streptococcus (GBS) causes invasive infections in human newborns. the GBS β-protein attenuates innate immune responses by binding to sialic acid-binding immunoglobulin-like lectin 5 (Siglec-5), an inhibitory receptor on phagocytes.the polymorphism could influence the risk of prematurity among human fetuses of mothers colonized with GBS. This first functionally proven example of a paired receptor system in the Siglec family has multiple implications for regulation of host immunity.

Amino Acid Sequence: 

Glu17-Thr434

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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