Product Name:

NebuSelect™ Recombinant Mouse P-Selectin/CD62P, His-tag

Catalog#:

NBL-242133

Description:

NebuSelect™ Recombinant Mouse P-Selectin/CD62P, His-tag(Cat#NBL-242133) is expressed in HEK293 with His tag at the C-Terminus.It contains Trp42-Ala709.

Species:

Mouse

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 81.1 kDa. Due to glycosylation, the protein migrates to 110-130 kDa based on Bis-Tris PAGE result.

Target Name:

P-Selectin/CD62P; FLJ45155; GMP140; GRMP; PADGEM; PSEL; P-Selectin; SELP; CD62P; CD62; LECAM3

Target Information:

P-selectin is critical in the progression of atherosclerosis as evidenced by knockout animal models where P-selectin knockout mice crossed with apoE deficient mice exhibit significantly reduced atherosclerosis and leukocyte recruitment in the plaque. A soluble form of P-selectin also exists, which may have pro-atherogenic and pro-thrombotic effects. Thus targeting of P-selectin remains a strong clinical candidate for developing novel therapeutic strategies in inflammatory diseases.

Amino Acid Sequence: 

Trp42-Ala709

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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