Product Name:

NebuSelect™ Recombinant Human NKp30/NCR3/CD337, hFc-tag

Catalog#:

NBL-242243

Description:

NebuSelect™ Recombinant Human NKp30/NCR3/CD337, hFc-tag(Cat#NBL-242243) is expressed in HEK293 with hFc tag at the C-Terminus.It contains Leu19-Thr138.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 39.8 kDa. Due to glycosylation, the protein migrates to 53-60 kDa based on Bis-Tris PAGE result.

Target Name:

NKp30/NCR3/CD337; CD337; LY117; NCR3; NKp30; 1C7; MALS

Target Information:

NKp30, along with NKp44 and NKp46, constitute a group of receptors termed "Natural Cytotoxicity Receptors". These receptors play a major role in triggering NK-mediated killing of most tumor cells lines.NKp30 stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also promotes myeloid dendritic cells (DC) maturation, both through killing DCs that did not acquire a mature phenotype, and inducing the release by NK cells of TNFA and IFNG which promote DC maturation.

Amino Acid Sequence: 

Leu19-Thr138

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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