Product Name: Human ANGPT2 Antibody (Zansecimab, Research Use)
Catalog Number: NBR-0510
Target Name: ANGPT2
Trade Name: Zansecimab
Antibody Drug Description: Zansecimab is a humanized IgG4 isotype antibody that neutralizes phospho-Tie2 induction due to Ang2, thereby stopping angiogenesis. The mechanism behind the neutralization is due to the antibody binding with high affinity to, and inhibiting Ang2. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: ANGPT2
Synonyms: Ang2
Target Description: Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1.
Ensembl: ENSG00000091879
Uniprot: O15123