Product Name: Human IL-12b Antibody (Ebdarokimab, Research Use)
Catalog Number: NBR-0599
Target Name: IL-12b
Trade Name: Ebdarokimab
Antibody Drug Description: Ebdarokimab is a fully human monoclonal antibody (mAb) targeting IL-12/IL-23 pathway. It specifically binds to the P40 subunit of both IL-12 and IL-23, resulting in inhibition of the signaling of IL-12 and IL-23 cytokines. Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS：N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG

  Gene Name: IL-12b
Synonyms: CLMF2; NKSF2; CLMF
Target Description: IL12B (Interleukin 12B) is a Protein Coding gene. Diseases associated with IL12B include Immunodeficiency 29 and Takayasu Arteritis. Among its related pathways are MIF Mediated Glucocorticoid Regulation and TGF-Beta Pathway. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and protein heterodimerization activity.
Ensembl: ENSG00000113302
Uniprot: P29460