
【Introduction】
Product Name: Human DLL4 Antibody (Enoticumab, Research Use)
Catalog Number: NBR-0609
Target Name: DLL4
Trade Name: Enoticumab
Antibody Drug Description: Enoticumab (REGN421) is a fully human IgG1 monoclonal antibody that binds human Dll4 and disrupts Notch-mediated signaling.
【Description】
Appearance: Transparent Liquid
Molecular Weight: ~150kDa
CAS:N/A
Solubility: Water; PBS, TBS Buffer etc.
Expression System: CHO Expressed
Isotype of Ab: Ab. Isotype - IgG
【Gene Information】
Gene Name: DLL4
Synonyms: Drosophila Delta Homolog 4; Delta-Like Protein 4; Delta4
Target Description: DLL4 (Delta Like Canonical Notch Ligand 4) is a Protein Coding gene. Diseases associated with DLL4 include Adams-Oliver Syndrome 6 and Adams-Oliver Syndrome. Among its related pathways are NOTCH2 Activation and Transmission of Signal to the Nucleus and Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants. Gene Ontology (GO) annotations related to this gene include calcium ion binding and Notch binding.
Ensembl: ENSG00000128917
Uniprot: Q9NR61