Product Name:

NebuSelect™ Recombinant Human EPHB2, His-tag

Catalog#:

NBL-240710

Description:

NebuSelect™ Recombinant Human EPHB2, His-tag(Cat#NBL-240710) is expressed in HEK293 with His tag at the C-Terminus.It contains Val19-Leu543.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 59.2 kDa. Due to glycosylation, the protein migrates to 65-75 kDa based on Bis-Tris PAGE result.

Target Name:

EPHB2; DRT; ERK; HEK5; TYRO5; CAPB; EK5; EPHT3; PCBC; Cek5; EphB2; EPHT3MGC87492; Nuk; Qek2; Sek3

Target Information:

EphB2, a receptor tyrosine kinase for ephrin ligands, is overexpressed in various cancers and plays an important role in tumor progression. EPHB2 promotes endothelial-mesenchymal transition (EMT) and elicits associated pathologic characteristics of glioblastoma multiforme (GBM) such as invasion and migration. EPHB2 is epigenetically overexpressed in hypoxia, a condition highly prevalent in malignancy. Furthermore, HIF-2α is required for EPHB2 stabilization by hypoxia.

Amino Acid Sequence: 

Val19-Leu543

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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