Product Name:

NebuSelect™ Recombinant Human CDH17/Cadherin 17, His-tag

Catalog#:

NBL-240715

Description:

NebuSelect™ Recombinant Human CDH17/Cadherin 17, His-tag(Cat#NBL-240715) is expressed in HEK293 with His tag at the C-terminus.It contains Gln23-Met787.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 86.1 kDa. Due to glycosylation, the protein migrates to 90-115 kDa based on Bis-Tris PAGE result.

Target Name:

CDH17/Cadherin 17; Cadherin-17; BILL-cadherin; LI-cadherin; P130; Cdh17; CDH16; HPT-1; cadherin-16; FLJ26931; MGC138218; MGC142024

Target Information:

Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades. In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.

Amino Acid Sequence: 

Gln23-Met787

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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