Product Name:

NebuSelect™ Recombinant Human OSMR, His-tag

Catalog#:

NBL-240732

Description:

NebuSelect™ Recombinant Human OSMR, His-tag(Cat#NBL-240732) is expressed in HEK293 with His tag at the C-Terminus.It contains Glu28-Met740.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 82.2 kDa. Due to glycosylation, the protein migrates to 110-140 kDa based on Bis-Tris PAGE result.

Target Name:

OSMR; IL-31R subunit beta; IL-31R-beta; IL-31RB; OSMR beta; OSMR; OSMRB; OSMRBMGC150626; PLCA1

Target Information:

OSMR is targeted to the mitochondrial matrix via the presequence translocase-associated motor complex components, mtHSP70 and TIM44. OSMR interacts with NADH ubiquinone oxidoreductase 1/2 (NDUFS1/2) of complex I and promotes mitochondrial respiration. Deletion of OSMR impairs spare respiratory capacity, increases reactive oxygen species, and sensitizes BTSCs to IR-induced cell death.

Amino Acid Sequence: 

Glu28-Met740

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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