Product Name:

NebuSelect™ Recombinant Human LILRB1/CD85j/ILT2, hFc-tag

Catalog#:

NBL-240761

Description:

NebuSelect™ Recombinant Human LILRB1/CD85j/ILT2, hFc-tag(Cat#NBL-240761) is expressed in HEK293 with hFc tag at the C-Terminus.It contains Gly24-Arg457.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 73.8 kDa. Due to glycosylation, the protein migrates to 78-105 kDa based on Bis-Tris PAGE result.

Target Name:

LILRB1/CD85j/ILT2; ILT2; ILT-2; ILT2FLJ37515; LILRB1; LIR1; MIR7; CD85J; XXbac-BCX85G21.4

Target Information:

LILRB1, also known as CD85j and ILT2, is a 110 kDa transmembrane glycoprotein in the LILR immunoregulatory protein family. Mature human LILRB1 consists of a 438 amino acid (aa) extracellular domain (ECD) with 4 tandem Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 4 inhibitory ITIM motifs.LILRB1 is a receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles. Receptor for H301/UL18, a human cytomegalovirus class I MHC homolog. Ligand binding results in inhibitory signals and down-regulation of the immune response.

Amino Acid Sequence: 

Gly24-Arg457

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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