Product Name:

NebuSelect™ Recombinant Human CDH17/Cadherin 17 Domain 3&4, mFc-tag

Catalog#:

NBL-240796

Description:

NebuSelect™ Recombinant Human CDH17/Cadherin 17 Domain 3&4, mFc-tag(Cat#NBL-240796) is expressed in HEK293 with mFc (IgG1) tag at the C-Terminus.It contains Val245-Phe449.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 49.16 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result.

Target Name:

CDH17/Cadherin 17 Domain 3&4

Target Information:

Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.

Amino Acid Sequence: 

Val245-Phe449

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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