Product Name:

NebuSelect™ Recombinant Cynomolgus TNF alpha, His-tag

Catalog#:

NBL-240801

Description:

NebuSelect™ Recombinant Cynomolgus TNF alpha, His-tag(Cat#NBL-240801) is expressed in HEK293 with His tag at the N-Terminus.It contains Val77-Leu233.

Species:

Cynomolgus

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 18.35 kDa. Due to glycosylation, the protein migrates to 19-25 kDa based on Bis-Tris PAGE result.

Target Name:

TNF alpha

Target Information:

Tumor necrosis factor alpha (TNF-alpha), also known as cachectin and TNFSF2, is the prototypic ligand of the TNF superfamily. It is a pleiotropic molecule that plays a central role in inflammation, immune system development, apoptosis, and lipid metabolism.Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation.

Amino Acid Sequence: 

Val77-Leu233

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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