Product Name:

NebuSelect™ Recombinant Human FcRn, His-tag

Catalog#:

NBL-240868

Description:

NebuSelect™ Recombinant Human FcRn, His-tag(Cat#NBL-240868) is expressed in HEK293 with His tag at the C-Terminus.It contains Ala24-Ser297(FCGRT) & Ile21-Met119(B2M).

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 31.5 kDa (FCGRT)&11.7 kDa (B2M). Due to glycosylation, the protein migrates to 35-40 kDa (FCGRT)&13-14 kDa (B2M) based on Bis-Tris PAGE result.

Target Name:

FcRn; FcRn alpha chain; FCGRT; FCRN; FCGRT&B2M

Target Information:

The neonatal Fc receptor (FCRN) is an approximately 45 kDa transmembrane glycoprotein with structural homology to MHC class I proteins. It is widely expressed in endothelial and epithelial cells and plays an important role in IgG homeostasis and antigen presentation by dendritic cells.FCGRT&B2M heterodimer protein (FcRn complex) consist of two subunits: p51, and p14 , and forms an MHC class I-like heterodimer.

Amino Acid Sequence: 

Ala24-Ser297(FCGRT) & Ile21-Met119(B2M)

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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