Product Name:

NebuSelect™ Recombinant Biotinylated Human IL-17A&F, Avi-His-tag

Catalog#:

NBL-241000

Description:

NebuSelect™ Recombinant Biotinylated Human IL-17A&F, Avi-His-tag(Cat#NBL-241000) is expressed in HEK293 with His tag and Avi tag at the C-Terminus.It contains Gly24-Ala155 (IL-17A) and Arg31-Gln163 (IL-17F).

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 15.1 kDa (IL-17A) and 17.5 kDa (IL-17F). Due to glycosylation, the protein migrates to 16 kDa and 27 kDa based on Bis-Tris PAGE result.

Target Name:

IL-17A&F; IL-17A；Interleukin-17A；CTLA-8；IL-17；IL-17F；IL24；ML-1；Interleukin-17F

Target Information:

Interleukin‑17A (IL‑17A), also known as CTLA‑8, is a 15‑20 kDa glycosylated cytokine that plays an important role in anti‑microbial and chronic inflammation. The six IL‑17 cytokines (IL‑17A‑F) are encoded by separate genes but adopt a conserved cystine knot fold.IL-17A is a ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC. Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines.

Amino Acid Sequence: 

Gly24-Ala155(IL-17A) & Arg31-Gln163(IL-17F)

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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