Product Name:

NebuSelect™ Recombinant Mouse IL-17RB, His-tag

Catalog#:

NBL-241007

Description:

NebuSelect™ Recombinant Mouse IL-17RB, His-tag(Cat#NBL-241007) is expressed in HEK293 with His tag at the C-Terminus.It contains Arg18-Gly286.

Species:

Mouse

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 30.9 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result.

Target Name:

IL-17RB; IL-17 receptor B; IL-17RB; IL-17ER; Evi27; IL-17 RH1; IL-17ER; IL17RB

Target Information:

Among inflammatory mediators, a growing body of evidence emphasizes the contribution of the interleukin 17 (IL-17) cytokine family in malignant diseases. Besides IL-17A, the prototypic member of the IL-17 family, several experimental findings strongly support the role of the IL-17B/IL-17 receptor B (IL-17RB) pathway in tumorigenesis and resistance to anticancer therapies. In mouse models, IL-17B signaling through IL-17RB directly promotes cancer cell survival, proliferation, and migration, and induces resistance to conventional chemotherapeutic agents.

Amino Acid Sequence: 

Arg18-Gly286

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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