Product Name:

NebuSelect™ Recombinant Biotinylated Human B7-H3 (4Ig) /B7-H3b, Avi-His-tag

Catalog#:

NBL-241049

Description:

NebuSelect™ Recombinant Biotinylated Human B7-H3 (4Ig) /B7-H3b, Avi-His-tag(Cat#NBL-241049) is expressed in HEK293 with His tag and Avi tag at the C-Terminus.It contains Gly27-Thr461.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 49.5 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Bis-Tris PAGE result.

Target Name:

B7-H3 (4Ig)/B7-H3b; B7-H3; CD276; PSEC0249;-4Ig-B7-H3; UNQ309; PRO352; B7 homolog 3; CD276

Target Information:

B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction.

Amino Acid Sequence: 

Gly27-Thr461

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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