Product Name:

NebuSelect™ Recombinant Human B2M/beta 2-Microglobulin, His-tag

Catalog#:

NBL-241052

Description:

NebuSelect™ Recombinant Human B2M/beta 2-Microglobulin, His-tag(Cat#NBL-241052) is expressed in HEK293 with His tag at the C-Terminus.It contains Ile21-Met119.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 12.8 kDa. Due to glycosylation, the protein migrates to 13-15 kDa based on Bis-Tris PAGE result.

Target Name:

B2M/beta 2-Microglobulin; Beta-2-microglobulin；B2M

Target Information:

The genetic and functional analysis of β2-microglobulin (B2M), a component of the HLA class-I complex.Acquired homozygous loss of B2M that caused lack of cell-surface HLA Class I expression in the tumor and a matched patient-derived xenograft (PDX). Downregulation of B2M was also found in two additional PDXs established from ICI-resistant tumors.

Amino Acid Sequence: 

Ile21-Met119

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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