Product Name:

NebuSelect™ Recombinant Biotinylated Human AXL, Avi-His-tag

Catalog#:

NBL-241053

Description:

NebuSelect™ Recombinant Biotinylated Human AXL, Avi-His-tag(Cat#NBL-241053) is expressed in HEK293 with His tag and Avi tag at the C-Terminus.It contains Ala26-Pro449.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 48.7 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Bis-Tris PAGE result.

Target Name:

AXL; Axl; UFO; AXL oncogene; AXL; ARK; JTK11; Tyro7; AI323647; EC 2.7.10; EC 2.7.10.1

Target Information:

Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell proliferation, chemotherapy resistance, invasion, and metastasis in several human cancers, such as lung, breast, and pancreatic cancers.

Amino Acid Sequence: 

Ala26-Pro449

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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