Product Name:

NebuSelect™ Recombinant Cynomolgus Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer, His-tag

Catalog#:

NBL-241121

Description:

NebuSelect™ Recombinant Cynomolgus Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer, His-tag(Cat#NBL-241121) is expressed in HEK293 with His tag at the C-terminus.It contains Tyr30-Pro1130 (ITGA2) acidic tail and Gln161-Asp868 (ITGB1) basic tail.

Species:

Cynomolgus

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 126.69 kDa (ITGA2) and 83.16 kDa (ITGB1). Due to glycosylation, the protein migrates to 130-170 kDa (ITGA2) and 100-130 kDa (ITGB1) based on Bis-Tris PAGE result.

Target Name:

Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer

Target Information:

The α2β1 integrin, also known as VLA-2, GPIa-IIa, CD49b, was first identified as an extracellular matrix receptor for collagens and/or laminins. It is now recognized that the α2β1 integrin serves as a receptor for many matrix and nonmatrix molecules. It plays a critical role in platelet function and homeostasis.

Amino Acid Sequence: 

Tyr30-Pro1130(ITGA2) acidic tail & Gln161-Asp868(ITGB1) basic tail

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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