Product Name:

NebuSelect™ Recombinant Human/Cynomolgus Activin RIIB/ACVR2B, mFc-tag

Catalog#:

NBL-241149

Description:

NebuSelect™ Recombinant Human/Cynomolgus Activin RIIB/ACVR2B, mFc-tag(Cat#NBL-241149) is expressed in HEK293 with mFc (IgG1) tag at the C-terminus.; It contains Ser19-Thr137 (Human) / Ser40-Thr158 (Cynomolgus).

Species:

Human/Cynomolgus

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 39.32 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Bis-Tris PAGE result.

Target Name:

Activin RIIB/ACVR2B

Target Information:

ActRIIB (activin receptor type-2B) is an activin receptor subtype constitutively expressed in the whole body, playing a role in cellular proliferation, differentiation, and metabolism. For its various physiological activities, ActRIIB interacts with activin and multiple other ligands including myostatin (MSTN), growth differentiation factor 11 (GDF11), and bone morphogenetic protein 9 (BMP9).

Amino Acid Sequence: 

Ser19-Thr137 (Human) / Ser40-Thr158 (Cynomolgus)

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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