Product Name:

NebuSelect™ Recombinant Human GCGR/Glucagon receptor, hFc-tag

Catalog#:

NBL-241152

Description:

NebuSelect™ Recombinant Human GCGR/Glucagon receptor, hFc-tag(Cat#NBL-241152) is expressed in HEK293 with hFc tag at the C-terminus.It contains Ala26-Lys136.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 39.00 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result.

Target Name:

GCGR/Glucagon receptor

Target Information:

The pancreatic hormone glucagon activates the glucagon receptor (GCGR), a class B seven-transmembrane G protein-coupled receptor that couples to the stimulatory heterotrimeric G protein and provokes PKA-dependent signaling cascades vital to hepatic glucose metabolism and islet insulin secretion. The GCGR expressed at the plasma membrane is constitutively ubiquitinated and upon agonist-activation, internalized GCGRs are deubiquitinated at early endosomes and recycled via Rab4-containing vesicles.

Amino Acid Sequence: 

Ala26-Lys136

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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