Product Name:

NebuSelect™ Recombinant Human Her2/ErbB2 (S310F), His-tag

Catalog#:

NBL-241154

Description:

NebuSelect™ Recombinant Human Her2/ErbB2 (S310F), His-tag(Cat#NBL-241154) is expressed in HEK293 with His tag at the C-terminus.; It contains Thr23-Thr652 (S310F).

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 70.50 kDa. Due to glycosylation, the protein migrates to 80-110 kDa based on Bis-Tris PAGE result.

Target Name:

Her2/ErbB2 (S310F)

Target Information:

ErbB2, also called Neu and Her2 (human epidermal growth factor receptor 2), is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors. ErbB family members serve as receptors for the epidermal growth factor (EGF) family of growth factors.Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane.

Amino Acid Sequence: 

Thr23-Thr652 (S310F)

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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