Product Name:

NebuSelect™ Recombinant Biotinylated Human CD98, Avi-His-tag

Catalog#:

NBL-241243

Description:

NebuSelect™ Recombinant Biotinylated Human CD98, Avi-His-tag(Cat#NBL-241243) is expressed in HEK293 with His tag and Avi tag at the N-terminus.It contains Arg206-Ala630.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 49.75 kDa. Due to glycosylation, the protein migrates to 50-65 kDa based on Bis-Tris PAGE result.

Target Name:

CD98

Target Information:

The type II transmembrane protein CD98, best known as the heavy chain of the heterodimeric amino acid transporters (HAT), is required for the surface expression and basolateral localization of this transporter complex in polarized epithelial cells. CD98 also interacts with beta1 integrins resulting in an increase in their affinity for ligand. In this study we explored the role of the transmembrane and cytoplasmic domains of CD98 on integrin-dependent cell adhesion and migration in polarized renal epithelial cells.

Amino Acid Sequence: 

Arg206-Ala630

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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