Product Name:

NebuSelect™ Recombinant Human CEACAM-5/CD66e (145-322), His-tag

Catalog#:

NBL-241285

Description:

NebuSelect™ Recombinant Human CEACAM-5/CD66e (145-322), His-tag(Cat#NBL-241285) is expressed in HEK293 with His tag at the C-terminus; It contains Pro145-Pro322.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 20.66 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Bis-Tris PAGE result.

Target Name:

CEACAM-5/CD66e (145-322)

Target Information:

Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) was identified as a metastatic driver. CEACAM5 overproduction enriched for an epithelial gene expression pattern and facilitated tumor outgrowth at metastatic sites. Tissues from patients with metastatic breast cancer confirmed elevated levels of CEACAM5 in lung metastases relative to breast tumors, and an inverse correlation between CEACAM5 and the mesenchymal marker vimentin was demonstrated.

Amino Acid Sequence: 

Pro145-Pro322

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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