Product Name:

NebuSelect™ Recombinant Biotinylated Cynomolgus Siglec-10, Avi-His-tag

Catalog#:

NBL-241296

Description:

NebuSelect™ Recombinant Biotinylated Cynomolgus Siglec-10, Avi-His-tag(Cat#NBL-241296) is expressed in HEK293 with His tag and Avi tag at the C-terminus.It contains Thr17-Asn552.

Species:

Cynomolgus

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 61.71 kDa. Due to glycosylation, the protein migrates to 72-82 kDa based on Bis-Tris PAGE result.

Target Name:

Siglec-10

Target Information:

Siglec-10 is a ligand for CD52, the target of the therapeutic monoclonal antibody Alemtuzumab. It is also reported to bind to Vascular adhesion protein 1 (VAP-1) and to the co-stimulatory molecule CD24 also known as HSA (Heat-stable antigen).Siglecs (sialic acid binding Ig-like lectins) are I-type lectins that belong to the immunoglobulin superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by a varying number of Ig-like C2-type domains. Siglecs 5-11 constitute the CD33/Siglec-3 related group, and are differentially expressed in the hematopoietic system.

Amino Acid Sequence: 

Thr17-Asn552

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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