Product Name:

NebuSelect™ Recombinant Human CLEC4M/CD299, His-Flag-tag

Catalog#:

NBL-241311

Description:

NebuSelect™ Recombinant Human CLEC4M/CD299, His-Flag-tag(Cat#NBL-241311) is expressed in HEK293 with His tag and Flag tag at the N-terminus.It contains Gln71-Glu399.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 39.81 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result.

Target Name:

CLEC4M/CD299

Target Information:

CLEC4M, also known as DC-SIGNR, L-SIGN or CD209L, is a Ca2+-dependent C-type lectin. CLEC4M and its homologue DC-SIGN are encoded by the closely related lectin gene cluster on chromosome 19p13.3. higher expression of CLEC4M is associated with poor clinical prognosis in lung cancer patients and enhances the resistance of NSCLC cells to cisplatin. Inhibition of CLEC4M expression significantly increased cisplatin sensitivity, suggesting potential clinical significance for targeting CLEC4M in overcoming cisplatin resistance.

Amino Acid Sequence: 

Gln71-Glu399

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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