Product Name:

NebuSelect™ Recombinant Rat PDGF R beta/CD140b, His-tag

Catalog#:

NBL-241350

Description:

NebuSelect™ Recombinant Rat PDGF R beta/CD140b, His-tag(Cat#NBL-241350) is expressed in HEK293 with His tag at the C-terminus.It contains Leu32-Val531.

Species:

Rat

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 57.36 kDa. Due to glycosylation, the protein migrates to 80-110 kDa based on Bis-Tris PAGE result.

Target Name:

PDGF R beta/CD140b

Target Information:

PDGF is a major serum mitogen that can exist as a homo or hetero-dimeric protein consisting of disulfide-linked PDGF-A and PDGF-B chains. The PDGF-AA,PDGF-BB and PDGF-AB isoforms have been shown to bind to two distinct cell surface PDGF receptors with different affinities. Where as PDGF R alpha binds all three PDGF isoforms with high affinity, PDGF R beta binds PDGF-BB only with high-affinity. PDGF R plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. Plays a role in the migration of vascular smooth muscle cells and the formation of neointima at vascular injury sites.

Amino Acid Sequence: 

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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