Product Name:

NebuSelect™ Recombinant Human TDGF1/Cripto, His-tag

Catalog#:

NBL-241422

Description:

NebuSelect™ Recombinant Human TDGF1/Cripto, His-tag(Cat#NBL-241422) is expressed in HEK293 with His tag at the C-Terminus.It contains Leu31-Thr172.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 16.92 kDa. Due to glycosylation, the protein migrates to 23-30 kDa based on Bis-Tris PAGE result.

Target Name:

TDGF1/Cripto

Target Information:

TDGF1 (CRIPTO) is a member of the epidermal growth factor-Cripto-1/FRL-1/Cryptic (EGF/CFC) gene family and an obligate co-receptor involved in NODAL signaling, a developmental program implicated in midline, forebrain, and left-right axis development in model organisms. Cripto-1 is enriched in a subpopulation of embryonal, melanoma, prostate, and pancreatic cancer cells that possess stem-like characteristics. Therefore, Cripto-1 may play a role during developmental EMT, and it may also be involved in the reprogramming of differentiated tumor cells into cancer stem cells through the induction of an EMT program.

Amino Acid Sequence: 

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

To get more information, please contact us freely.