Product Name:

NebuSelect™ Recombinant Cynomolgus IGF1R/CD221, His-tag

Catalog#:

NBL-241550

Description:

NebuSelect™ Recombinant Cynomolgus IGF1R/CD221, His-tag(Cat#NBL-241550) is expressed in HEK293 with His tag at the C-Terminus.It contains Glu31-Asn908.

Species:

Cynomolgus

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 80.59 kDa (alpha subunit) and 19.28 kDa (beta subunit). Due to glycosylation, the protein migrates to 48-58 kDa (beta subunit) and 100-115 kDa (alpha subunit) and 130-150 kDa based on Bis-Tris PAGE result.

Target Name:

IGF1R/CD221

Target Information:

The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis protection. IGF signalling also influences hypoxia signalling, protease secretion, tumour cell motility and adhesion, and thus can affect the propensity for invasion and metastasis. Therefore, the IGF1R is now an attractive anti-cancer treatment target.

Amino Acid Sequence: 

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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