Product Name:

NebuSelect™ Recombinant Biotinylated Human CDH17/Cadherin 17 Domain 5-7, His-tag

Catalog#:

NBL-241576

Description:

NebuSelect™ Recombinant Biotinylated Human CDH17/Cadherin 17 Domain 5-7, His-tag(Cat#NBL-241576) is expressed in HEK293 with His tag at the C-Terminus.It contains Glu450-Gly777.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 36.79 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Bis-Tris PAGE result.

Target Name:

CDH17/Cadherin 17 Domain 5-7

Target Information:

Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.

Amino Acid Sequence: 

Glu450-Gly777

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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