Product Name:

NebuSelect™ Recombinant Biotinylated Human ALCAM/CD166 , His-tag

Catalog#:

NBL-241790

Description:

NebuSelect™ Recombinant Biotinylated Human ALCAM/CD166 , His-tag(Cat#NBL-241790) is expressed in HEK293 with His tag at the C-Terminus.It contains Trp28-Ala526.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 57 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Bis-Tris PAGE result.

Target Name:

ALCAM/CD166; CD166; ALCAM; MEMD; CD6L; KG-CAM

Target Information:

Brain metastasis (BM) in non-small-cell lung cancer (NSCLC) has a very poor prognosis. Recent studies have demonstrated the importance of cell adhesion molecules in tumor metastasis.Elevated levels of ALCAM expression promote BM formation in NSCLC through increased tumor cell dissemination and interaction with the brain endothelial cells. Therefore, ALCAM could be targeted to reduce the occurrence of BM.

Amino Acid Sequence: 

Trp28-Ala526

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

To get more information, please contact us freely.