Product Name:

NebuSelect™ Recombinant Cynomolgus M-CSF/CSF-1, His-tag

Catalog#:

NBL-241793

Description:

NebuSelect™ Recombinant Cynomolgus M-CSF/CSF-1, His-tag(Cat#NBL-241793) is expressed in HEK293 with His tag at the C-Terminus.It contains Glu33-Leu255.

Species:

Cynomolgus

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 26.26 kDa. Due to glycosylation, the protein migrates to 45-55 kDa based on Bis-Tris PAGE result.

Target Name:

M-CSF/CSF-1; CSF1; CSF-1; MCSF; M-CSF; MGC31930; Lanimostim

Target Information:

CSF-1, also known as M-CSF , is a four alpha -helical-bundle cytokine that is the primary regulator of macrophage survival, proliferation and differentiation. CSF-1 is also essential for the survival and proliferation of osteoclast progenitors.CSF-1 is cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. This mutation leads to a deletion of exons 2-7 of the EGFR gene and renders the mutant receptor incapable of binding any known ligand.

Amino Acid Sequence: 

Glu33-Leu255

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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