Product Name:

NebuSelect™ Recombinant Mouse Integrin alpha L beta 2 (ITGAL&ITGB2) Heterodimer, His-tag

Catalog#:

NBL-241850

Description:

NebuSelect™ Recombinant Mouse Integrin alpha L beta 2 (ITGAL&ITGB2) Heterodimer, His-tag(Cat#NBL-241850) is expressed in HEK293 with His tag at the C-Terminus.It contains Tyr24-His1087 (ITGAL) acidic tail & Gln24-Asn702 (ITGB2) basic tail.

Species:

Mouse

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 123.30 kDa (ITGAL) and 79.60 kDa (ITGB2). Due to glycosylation, the protein migrates to 160-180 kDa (ITGAL) and 90-105 kDa (ITGB2) based on Bis-Tris PAGE result.

Target Name:

Integrin alpha L beta 2 (ITGAL&ITGB2) Heterodimer

Target Information:

Integrin αLβ2 is one member of the integrin family and also called leukocyte function-associated antigen-1 (LFA-1). It is widely expressed on T lymphocytes and controls the function and, in particular, the migration of immune cells[1]. Active αLβ2 can bind ICAM­1/CD54, ICAM­2, ICAM3 and JAM­1[2].

Amino Acid Sequence: 

Tyr24-His1087 (ITGAL) acidic tail & Gln24-Asn702 (ITGB2) basic tail

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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