Product Name:

NebuSelect™ Recombinant Cynomolgus IL-12B/p40/NKSF2, His-tag

Catalog#:

NBL-241888

Description:

NebuSelect™ Recombinant Cynomolgus IL-12B/p40/NKSF2, His-tag(Cat#NBL-241888) is expressed in HEK293 with His tag at the C-Terminus.It contains Ile23-Ser328.

Species:

Cynomolgus

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 35.86 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result.

Target Name:

IL-12B/p40/NKSF2

Target Information:

Interleukin (IL)‑12B, which encodes the p40 subunit common to IL‑12 and IL‑23, as one of the genes for which expression in fibroblast‑like synoviocytes from patients with rheumatoid arthritis (RA‑FLS) is induced by DcR3.Decoy receptor 3 (DcR3) competitively binds to three ligands, Fas ligand, lymphotoxin‑related inducible ligand that competes for glycoprotein D binding to herpesvirus entry mediator on T cells and tumor necrosis factor‑like ligand 1A (TL1A), to prevent their effects. Recent studies have suggested that DcR3 directly affects cells as a ligand.

Amino Acid Sequence: 

Ile23-Ser328

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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