Product Name:

NebuSelect™ Recombinant Human TFPI-2, His-tag

Catalog#:

NBL-242041

Description:

NebuSelect™ Recombinant Human TFPI-2, His-tag(Cat#NBL-242041) is expressed in HEK293 with His tag at the C-Terminus.It contains Asp23-Lys213.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 22.9 kDa. Due to glycosylation, the protein migrates to 30-35 kDa based on Bis-Tris PAGE result.

Target Name:

TFPI-2; TFPI-2; PP5; TFPI2; REF1; TFPI-2REF1

Target Information:

Tissue factor pathway inhibitor-2 (TFPI-2) has previously been characterized as an endogenous anticoagulant. TFPI-2 is expressed in the vast majority of cells, mainly secreted into the extracellular matrix. Moreover, in sputum from cystic fibrosis patients TFPI-2 C-terminal fragments are generated and found associated with immunoglobulins. Together our data describe a previously unknown host defense mechanism and therapeutic importance of TFPI-2 against invading Gram-negative bacterial pathogens.

Amino Acid Sequence: 

Asp23-Lys213.

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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