Product Name:

NebuSelect™ Recombinant Human SPP1/OPN, His-tag

Catalog#:

NBL-242074

Description:

NebuSelect™ Recombinant Human SPP1/OPN, His-tag(Cat#NBL-242074) is expressed in HEK293 with His tag at the C-Terminus.It contains Ile17-Asn300.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 34.8 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Bis-Tris PAGE result.

Target Name:

SPP1/OPN; Osteopontin; Bone sialoprotein 1; Nephropontin; SPP-1; BNSP; OPN; SPP1; Uropontin; BSP-1; ETA-1; BSPI

Target Information:

Ovarian cancer is one of the most lethal malignant tumors in women. Secreted phosphoprotein 1 (SPP1) plays an important role in some cancer types. The expression of SPP1 was higher in epithelial ovarian cancer tissues than in normal ovarian tissues. Silencing SPP1 decreased the cell proliferation, migration, and invasion. Ectopic expression of SPP1 increased the cell proliferation, migration, and invasion. Silencing SPP1 prevented ovarian cancer growth in mice. Silencing SPP1 inhibited Integrin β1/FAK/AKT pathway.

Amino Acid Sequence: 

Ile17-Asn300

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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