Product Name:

NebuSelect™ Recombinant Biotinylated Human Siglec-8, Avi-His-tag

Catalog#:

NBL-242106

Description:

NebuSelect™ Recombinant Biotinylated Human Siglec-8, Avi-His-tag(Cat#NBL-242106) is expressed in HEK293 with His tag and Avi tag at the C-Terminus.It contains Met17-Ala363.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 40.7 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Bis-Tris PAGE result.

Target Name:

Siglec-8; CDw329; MGC59785; SAF2; SAF2SAF-2; Siglec-8; SIGLEC8L; SIGLEC8

Target Information:

Siglec-8, also known as SAF, is an approximately 75 kDa transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory molecules. Mature human Siglec-8 consists of a 347 amino acid (aa) extracellular domain (ECD) with three Ig-like domains.Putative adhesion molecule that mediates sialic-acid dependent binding to red blood cells. Preferentially binds to alpha-2,3-linked sialic acid. Also binds to alpha-2,6-linked sialic acid.

Amino Acid Sequence: 

Met17-Ala363

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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