Product Name:

NebuSelect™ Recombinant Human SEMA3A, His-tag

Catalog#:

NBL-242131

Description:

NebuSelect™ Recombinant Human SEMA3A, His-tag(Cat#NBL-242131) is expressed in HEK293 with His tag at the N-Terminus.It contains Asn21-Val771.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 87.7 kDa. Due to cleavage site, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.

Target Name:

SEMA3A; Semaphorin-3A; Semaphorin III; Sema III; Semaphorin-D; Sema D; coll-1; collapsin 1; Hsema-I; Hsema-III; MGC133243; SEMA1, Sema3A; SEMAD; SEMAIII; SEMAL; semaphorin L

Target Information:

The CRMP proteins were originally identified as mediators of Sema3A signaling and neuronal differentiation. Much has been learned about the mechanism by which CRMPs regulate cellular responses to Sema3A.The secreted protein Sema3A (collapsin-1) was the first identified vertebrate semaphorin. Sema3A acts primarily as a repulsive axon guidance cue, and can cause a dramatic collapse of the growth cone lamellipodium.Neuropilin-1 (NP1) and members of the class A plexins (PlexA) form a Sema3A receptor complex, with NP1 serving as a high-affinity ligand binding partner, and PlexA transducing the signal into the cell via its large intracellular domain.

Amino Acid Sequence: 

Asn21-Val771

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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