Product Name:

NebuSelect™ Recombinant Human PSMP, hFc-tag

Catalog#:

NBL-242177

Description:

NebuSelect™ Recombinant Human PSMP, hFc-tag(Cat#NBL-242177) is expressed in HEK293 with hFc tag at the C-Terminus.It contains Lys37-Ser139.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 37.9 kDa. Due to glycosylation, the protein migrates to 45-50 kDa based on Bis-Tris PAGE result.

Target Name:

PSMP; Msmp; Psmp

Target Information:

PC3-secreted microprotein (PSMP)/microseminoprotein (MSMP) is a novel chemotactic cytokine and its receptor is CCR2. PSMP was highly expressed in fibrotic/cirrhotic tissues from patients with different etiologies of liver disease and in the 3 experimental mouse models of fibrosis. Damage-associated molecular pattern molecules HMGB-1 and IL-33 induced hepatocytes to produce PSMP. PSMP promotes liver fibrosis through inflammatory macrophage infiltration, polarization and production of proinflammatory cytokines, as well as direct activation of hepatic stellate cells via its receptor CCR2.

Amino Acid Sequence: 

Lys37-Ser139

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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