Product Name:

NebuSelect™ Recombinant Biotinylated Human PLAU/uPA (active form), Avi-His-tag

Catalog#:

NBL-242190

Description:

NebuSelect™ Recombinant Biotinylated Human PLAU/uPA (active form), Avi-His-tag(Cat#NBL-242190) is expressed in HEK293 with His tag and Avi tag at the C-Terminus.It contains Ser21-Leu431, which consists of two chains: Long chain A (Ser21-Phe177) and chain B (Ile179-Leu 431). The long chain A is further cleaved to yield a short chain A (Lys156-Phe 177) and N-Terminus fragment (Ser21-Lys155).

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 49.3 kDa. Due to protein lysis and glycosylation, the protein migrates to 24-26 kDa(long chain A), 35-38 kDa(chain B) and 52-60 kDa(long chain A&chain B) based on Bis-Tris PAGE result.

Target Name:

PLAU/uPA; PLAU; Urokinase; ATF; UPA; URK; u-PA; BDPLT5; QPD

Target Information:

Plasminogen activator, urokinase (uPA) is a secreted serine protease whose Dysregulation is often accompanied by various cancers. PLAU inhibition could suppress tumor growth. Collectively, PLAU is necessary for tumor progression and can be a diagnostic and prognostic biomarker in HNSCC.

Amino Acid Sequence: 

Ser21-Leu431

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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