Product Name:

NebuSelect™ Recombinant Human Integrin alpha X beta 2 (ITGAX&ITGB2) Heterodimer, His-tag

Catalog#:

NBL-242421

Description:

NebuSelect™ Recombinant Human Integrin alpha X beta 2 (ITGAX&ITGB2) Heterodimer, His-tag(Cat#NBL-242421) is expressed in HEK293 with His tag at the C-Terminus.It contains Phe20-Pro1107(ITGAX) acidic tail & Gln23-Asn700(ITGB2) basic tail.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 125.50 kDa (ITGAX) and 79.50 kDa (ITGB2). Due to glycosylation, the protein migrates to 130-135 kDa (ITGAX) and 85-95 kDa (ITGB2) based on Bis-Tris PAGE result.

Target Name:

Integrin alpha X beta 2 (ITGAX&ITGB2) Heterodimer; CD11C; SLEB6; CD18; ITGAX&ITGB2; ITGA; ITGB2

Target Information:

The integrin alpha X beta 2 (CD11c/CD18, p150,95) binds ligands through the I domain of the alpha X subunit. Ligands include the complement factor fragment iC3b, a key component in the innate immune defense, which, together with the expression of alpha X beta 2 on dendritic cells and on other leukocytes, suggests a role in the immune response.

Amino Acid Sequence: 

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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