Product Name:

NebuSelect™ Recombinant Mouse IGFBP-3R, hFc-tag

Catalog#:

NBL-242518

Description:

NebuSelect™ Recombinant Mouse IGFBP-3R, hFc-tag(Cat#NBL-242518) is expressed in HEK293 with hFc tag at the C-Terminus.It contains Gly39-Arg204.

Species:

Mouse

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 44.4 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.

Target Name:

IGFBP-3R; IGFBP-3R; GFBP3R; LOC124446; TMEM219

Target Information:

Insulin-like growth factor-binding protein-3 (IGFBP-3) is a multifunctional protein known for modulating mitogenic and metabolic actions of IGFs as well as exerting a variety of biological actions not involving IGF. IGFBP-3 inhibits airway inflammation and hyper-responsiveness via an IGF-independent mechanism that involves activation of IGFBP-3R signaling and cross-talk with NF-κB signaling. The IGFBP-3/IGFBP-3R system therefore plays a pivotal role in the pathogenesis of asthma and can serve as a newly identified potential therapeutic target for this debilitating disease.

Amino Acid Sequence: 

Gly39-Arg204

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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