Product Name:

NebuSelect™ Recombinant Human GFRAL/GFR alpha-like, hFc-tag

Catalog#:

NBL-242590

Description:

NebuSelect™ Recombinant Human GFRAL/GFR alpha-like, hFc-tag(Cat#NBL-242590) is expressed in HEK293 with hFc tag at the C-Terminus.It contains Ser19-Glu351.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 64.6 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Bis-Tris PAGE result.

Target Name:

GFRAL/GFR alpha-like; GFR alpha-like; GFRAL; GRAL; C6orf144

Target Information:

GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain, a 20 aa transmembrane domain and a 23 aa cytoplasmic domain.GFRAL is a brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses.

Amino Acid Sequence: 

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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