Product Name:

NebuSelect™ Recombinant Human Coagulation factor XI, His-tag

Catalog#:

NBL-242615

Description:

NebuSelect™ Recombinant Human Coagulation factor XI, His-tag(Cat#NBL-242615) is expressed in HEK293 with His tag at the C-Terminus.It contains Glu19-Val625.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 69.1 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Bis-Tris PAGE result.

Target Name:

Coagulation factor XI; Coagulation factor XI; FXI; PTA; F11

Target Information:

Coagulation factor (F)XI has been described as a component of the early phase of the contact pathway of blood coagulation, acting downstream of factor XII.In contrast to its mild hemostatic activities, FXI is known to play a significant role in thrombosis, as it is a demonstrated independent risk factor for deep vein thrombosis, ischemic stroke, and myocardial infarction. A better understanding of the varied and complex role of FXI in both thrombosis and hemostasis will help to allow better prediction of bleeding risk in FXI-deficient patients and also informing the development of targeted agents to inhibit the thrombotic activities of FXI while preserving hemostasis.

Amino Acid Sequence: 

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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