Product Name:

NebuSelect™ Recombinant Mouse GITR Ligand/TNFSF18, hFc-tag

Catalog#:

NBL-242620

Description:

NebuSelect™ Recombinant Mouse GITR Ligand/TNFSF18, hFc-tag(Cat#NBL-242620) is expressed in HEK293 with hFc tag at the N-Terminus.It contains Thr47-Ser173.

Species:

Mouse

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 41.8 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Bis-Tris PAGE result.

Target Name:

GITR Ligand/TNFSF18; TNFSF18; AITRL; TL6; GITRL; GITR Ligand

Target Information:

Glucocorticoid-induced TNFR-related protein (TNFRSF18, GITR, CD357), expressed by T cells, and its ligand (TNFSF18, GITRL), expressed by myeloid populations, provide co-stimulatory signals that boost T cell activity. Due to the important role that GITR plays in regulating immune functions, agonistic stimulation of GITR is a promising therapeutic concept.

Amino Acid Sequence: 

Thr47-Ser173

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

To get more information, please contact us freely.