Product Name:

NebuSelect™ Recombinant Biotinylated Human GITR Ligand/TNFSF18 Trimer , His-Flag-tag

Catalog#:

NBL-242622

Description:

NebuSelect™ Recombinant Biotinylated Human GITR Ligand/TNFSF18 Trimer , His-Flag-tag(Cat#NBL-242622) is expressed in HEK293 with His tag and flag tag at the N-Terminus.It contains Gln50-Ser177.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 47.5 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Bis-Tris PAGE result.

Target Name:

GITR Ligand/TNFSF18 Trimer; TNFSF18; AITRL; TL6; GITRL; GITR Ligand

Target Information:

Glucocorticoid-induced TNFR-related protein (TNFRSF18, GITR, CD357), expressed by T cells, and its ligand (TNFSF18, GITRL), expressed by myeloid populations, provide co-stimulatory signals that boost T cell activity. Due to the important role that GITR plays in regulating immune functions, agonistic stimulation of GITR is a promising therapeutic concept.

Amino Acid Sequence: 

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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