Product Name:

NebuSelect™ Recombinant Human FOLR4/Juno, His-tag

Catalog#:

NBL-242633

Description:

NebuSelect™ Recombinant Human FOLR4/Juno, His-tag(Cat#NBL-242633) is expressed in HEK293 with His tag at the C-Terminus.It contains Gly20-Ser228.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 25 kDa. Due to glycosylation, the protein migrates to 30-35 kDa based on Bis-Tris PAGE result.

Target Name:

FOLR4/Juno; Folate receptor 4; FR-delta; Izumo1r; Folbp3; Juno; FOLR4, LOC390243

Target Information:

Izumo1 is the only essential sperm-egg fusion protein currently known on mammalian sperm, and its egg receptor (Juno; formerly Folr4) was recently discovered. Male knockout mice for Izumo1 and female knockout mice for Juno are both healthy but sterile. Here, both sperm-egg binding proteins are shown to be evolving under positive selection. Juno's presence in mammals alone, suggesting a recent mammalian-specific duplication and neofunctionalization of the ancestral folate receptor.

Amino Acid Sequence: 

Gly20-Ser228

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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