Product Name:

NebuSelect™ Recombinant Human FGFR4, hFc-tag

Catalog#:

NBL-242670

Description:

NebuSelect™ Recombinant Human FGFR4, hFc-tag(Cat#NBL-242670) is expressed in HEK293 with hFc tag at the C-Terminus.It contains Leu22-Asp369.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 65.3 kDa. Due to glycosylation, the protein migrates to 80-95 kDa based on Bis-Tris PAGE result.

Target Name:

FGFR4; CD334; FGF R4; FGFR4; FGFR-4; MGC20292; JTK2; TKF

Target Information:

Fibroblast growth factor receptor 4 (FGF R4), also known as CD334, is a 110 kDa glycosylated transmembrane receptor tyrosine kinase.Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays a role in the regulation of cell proliferation, differentiation and migration, and in regulation of lipid metabolism, bile acid biosynthesis, glucose uptake, vitamin D metabolism and phosphate homeostasis. Required for normal down-regulation of the expression of CYP7A1, the rate-limiting enzyme in bile acid synthesis, in response to FGF19.

Amino Acid Sequence: 

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

To get more information, please contact us freely.