Product Name:

NebuSelect™ Recombinant Human FAM3D, hFc-tag

Catalog#:

NBL-242695

Description:

NebuSelect™ Recombinant Human FAM3D, hFc-tag(Cat#NBL-242695) is expressed in HEK293 with hFc tag at the C-Terminus.It contains Tyr26-Phe224.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 48.7 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Bis-Tris PAGE result.

Target Name:

FAM3D; EF7; FAM3D; OIT1

Target Information:

The physiological homeostasis of gut mucosal barrier is maintained by both genetic and environmental factors and its impairment leads to pathogenesis such as inflammatory bowel disease. A cytokine like molecule, FAM3D (mouse Fam3D), is highly expressed in mouse gastrointestinal tract. Here, we demonstrate that deficiency in Fam3D is associated with impaired integrity of colonic mucosa, increased epithelial hyper-proliferation, reduced anti-microbial peptide production and increased sensitivity to chemically induced colitis associated with high incidence of cancer.

Amino Acid Sequence: 

Tyr26-Phe224

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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