Product Name:

NebuSelect™ Recombinant Human Endoglin/CD105, Avi-His-tag

Catalog#:

NBL-242730

Description:

NebuSelect™ Recombinant Human Endoglin/CD105, Avi-His-tag(Cat#NBL-242730) is expressed in HEK293 with His tag and Avi tag at the C-Terminus.It contains Glu26-Gly586.

Species:

Human

Expression System:

HEK293

Molecular Weight: 

The protein has a predicted MW of 63.7 kDa. Due to glycosylation, the protein migrates to 70-82 kDa based on Bis-Tris PAGE result.

Target Name:

Endoglin/CD105; CD105; Endoglin; ENG; ORW; ORW1; END; HHT1

Target Information:

Endoglin (CD105) is a 90 kDa type I transmembrane glycoprotein of the zona pellucida (ZP) family of proteins. Endoglin is a vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature (PubMed:7894484). Regulates the migration of vascular endothelial cells. Required for normal extraembryonic angiogenesis and for embryonic heart development. May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis.

Amino Acid Sequence: 

Purity:

＞95%

Formulation:

see COA

Endotoxin:

＜1EU/ug(LAL Method)

Storage: 

4°C for short term. 

-20°C for long term.

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